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The era of monoclonal antibody-based therapeutics has arrived. Monoclonal antibodies of high quality targeting almost any antigen can now be engineered and manufactured in large quantities. In the clinic, monoclonal antibodies are proving to be safe and effective for the treatment of a wide range of diseases including rheumatoid arthritis, Crohn's disease, spondyloarthropathies, psoriasis and allograft rejection.

Type

Journal article

Journal

Curr Opin Biotechnol

Publication Date

12/2002

Volume

13

Pages

615 - 620

Keywords

Antibodies, Monoclonal, Arthritis, Rheumatoid, Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Child, Clinical Trials as Topic, Crohn Disease, Drug Approval, Graft Rejection, Humans, Immunotherapy, Active, Inflammation